Trump Administration Announces More Than $5 Billion for the Genesis Mission, a National Mission on AI for Science

Assistant to the President and Director of the White House Office of Science and Technology Policy Michael Kratsios unveiled more than $5 billion in Federal commitments expanding the Genesis Mission alongside new mission-driven National Science and Technology Challenges. Launched by President Trump’s Executive Order in November 2025 and led by the White House, the Genesis Mission is a national effort to harness AI for science. What began at the Department of Energy is now a whole-of-government initiative: More than 15 Federal agencies will contribute research awards, funding opportunities, specialized scientific datasets, and research facilities to the National Science and Technology Challenges. These agencies will leverage the DOE-built American Science and Security Platform, which provides shared infrastructure that connects researchers with data, compute, and AI tools to accelerate scientific discovery.